Endocrine Abstracts

Introduction: Pathophysiologic mechanisms that connect type 2 diabetes mellitus (T2DM) and chronic obstructive pulmonary disease (COPD) are complex and still unknown as are any respiratory effects of antidiabetic agents. COPD increases insulin resistance by chronic inflammation, hypoxia and corticosteroid treatment while, on the other hand, insulin as an anabolic hormone stimulates post-prandial protein synthesis and oxidative phosphorylation in skeletal muscle so that insulin...